Electromagnetic Field Exposure and Male Breast Cancer Risk: A Meta-analysis of 18 Studies
Jing-Wen Sun et al.
Abstract
Background: The possibility that electromagnetic fields (EMF) exposure may increase male breast cancer risk
has been discussed for a long time. However, arguments have been presented that studies limited by poor quality
could have led to statistically significant results by chance or bias. Moreover, data fo the last 10 years have not
been systematically summarized. Methods and Results: To confirm any possible association, a meta-analysis was
performed by a systematic search strategy. Totals of 7 case-control and 11 cohort studies was identified and pooled
ORs with 95% CIs were used as the principal outcome measures. Data from these studies were extracted with
a standard meta-analysis procedure and grouped in relation to study design, cut-off point, exposure assessment
method, adjustment and exposure model. A statistical significant increased risk of male breast cancer with EMF
exposure was defined (pooled ORs = 1.32, 95% CI = 1.14 -1.52, P < 0.001), and subgroup analyses also showed
similar results. Conclusions: This meta-analysis suggests that EMF exposure may be associated with the increase
risk of male breast cancer despite the arguments raised.
Key Words: Electromagnetic fields - male breast cancer - meta-analysis
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